React's title track peaked at number 36 on the Billboard Hot 100, but the album sold poorly and Sermon was dropped from the label in 2003.

[4] Sermon went on to establish his Def Squad imprint with Universal Records and released his sixth solo album, Chilltown, New York, in 2004.

The album was powered by the single "Feel It" (which contained a sample of reggae/R&B singer Sean Paul), a song which became a success in the United States.

However, Sermon has not stopped in the music industry, as he produced the song "Goldmine" on Busta Rhymes' album, The Big Bang in 2006.

He also collaborated with Redman and produced a few songs on the album Red Gone Wild while also making an appearance with Def Squad member Keith Murray.

MTV Raps in a freestyle session featuring artists such as Rakim, KRS-One, Chubb Rock, MC Serch and Craig Mack.