[2] Her work and activism has focused on the recognition of the sovereignty of the indigenous people of the Treaty 8 area of Canada.
[3] Deranger organized activism and indigenous protests against the expansion of the Athabasca oil sands in Alberta, Canada.
[4][6] The organization also developed resources for indigenous communities facing the effects of climate change.
[1][4][8][9] Deranger's parents were members of the American Indian Movement who met at the Wounded Knee Occupation.
[4][10] Deranger was one of three activists profiled in the 2012 documentary Elemental, which depicts her opposition to the Keystone Pipeline.