[1] Guldentops started his Humanities study at the 1960 at the Onze-Lieve-Vrouwcollege in Antwerpen, where he graduated in economics in 1967.
In 1969 he proceeded to study Computer science at the Karel De Grote Hogeschool, where he graduated in 1971.
Subsequently after another year at the Katholieke Universiteit Leuven, he received a Post-graduate degree in computer science.
[2] Guldentops started his career at the Society for Worldwide Interbank Financial Telecommunication (SWIFT) in 1974 as Chief Inspector, and was Director Information Security from 1996 to 2001.
From 1993 to 2001 he was also Vice President Research at the ISACA (Information Systems Audit and Control Association).