Ernei (Hungarian: Nagyernye [ˈnɒɟɛrɲɛ]) is a commune in Mureș County, Transylvania, Romania, composed of six villages: Călușeri (Székelykál), Dumbrăvioara (Sáromberke), Ernei, Icland (Ikland), Săcăreni (Székes), and Sângeru de Pădure (Erdőszengyel).

The commune is situated on the Transylvanian Plateau, on the left bank of the Mureș River.

Ernei is traversed by national road DN15 [ro], which connects Transylvania to Western Moldavia; the city of Reghin is 22 km (14 mi) to the north.

Ernei formed part of the Székely Land region of the historical Transylvania province.

Until 1876, it fell within Marosszék, thereafter until 1918, the village belonged to the Maros-Torda County of the Kingdom of Hungary.