Ernest Ndjissipou (born 24 September 1972, in Bangui) is a retired Central African long-distance and marathon runner.

[1] He represented the Central African Republic in three editions of the Olympic Games (1992, 1996, and 2004), and has also set both a national record and a personal best of 2:18:06 in men's marathon from the 2003 IAAF World Championships in Paris, France.

[2] Ndjissipou made his official debut as a long-distance runner in the men's 5000 metres at the 1992 Summer Olympics in Barcelona, where he finished twelfth in the last of four preliminary heats with a time of 14:40.12, trailing behind leader Salvatore Antibo of Italy by one minute and ten seconds.

[3] At the 1996 Summer Olympics in Atlanta, Ndjissipou extended his track and field resume by competing in the men's marathon.

Though he had never experienced road running in a global stage, Ndjissipou managed to claim a ninety-seventh spot successfully in a vast field of a hundred athletes with a time of 2:35:55.