Leo Brouwer, a classical guitarist, is her grandson, and gymnast-political scientist Rafael A. Lecuona, an anti-communist, was her nephew.

She studied music at the Centro Asturiano de La Habana and with French teacher Lucía Calderón.

[1] At the age of 15, Lecuona completed her first work Habanera Luisa, which was published widely in Cuba and Spain by Anselmo López in 1897.

In 1936 she was invited to New York City by the Pan American Union, where she accompanied the Mexican tenor Tito Guizar.

She traveled with her brother on tour, and sometimes played a duo for four hands with him at radio stations and concert venues, including Carnegie Hall in 1948.