Hudson has also acted in the films Leviathan (1989), The Hand That Rocks the Cradle (1992), The Crow (1994), Airheads (1994), The Basketball Diaries (1995), Congo (1995), Miss Congeniality (2000), and The Ron Clark Story (2006).

Elsewhere (1984), The Last Precinct (1986), 10-8: Officers on Duty (2003–2004), Desperate Housewives (2006–2007), The Secret Life of the American Teenager (2008–2013), Law & Order (2009–2010), the voice of Agent Bill Fowler in Transformers: Prime (2010–2013), Franklin & Bash (2012–2014), Grace and Frankie (2015–2020), and L.A.'s Finest (2019–2020).

Hudson joined the U.S. Marine Corps immediately after high school but was discharged after only three months on medical grounds due to asthma.

[3] Having moved to Detroit, he became the resident playwright at Concept East, the oldest black theater company in the United States.

He began a doctoral program at the University of Minnesota, Twin Cities before leaving to appear in a stage production of The Great White Hope.

He played Harry McDonald, the FBI superior of Sandra Bullock's character in the feature film Miss Congeniality (2000).

[8] Hudson appeared in the 2016 Ghostbusters reboot, playing Bill Jenkins, the uncle of Leslie Jones's lead character Pattie Tolan.

Hudson called it "a very different show", citing the duality of having to protect people as a member of law enforcement while having unresolved relationships that need to be reconciled.

[11] In August 2019, he confirmed his involvement in Ghostbusters: Afterlife directed by Jason Reitman, joining original cast members Sigourney Weaver, Dan Aykroyd, Bill Murray and Annie Potts.

[16] In January 2023, Hudson guest voiced a character, Grini Millegi, a Dowutin gangster who was an associate of Cid and oversees Riot Racing on the planet Safa Toma, on Star Wars: The Bad Batch.