She received critical acclaim and a Best Actress in a Leading Role trophy at Malaysia Film Festival twice for her portrayal of inspiring young sales girl and part time student Nurul Ain in Soal Hati (2001) and as Nora, an old lady with dark past in the film Hingga Hujung Nyawa (2005).

She received another three Malaysia Film Festival's Best Actress award nomination for her performance in Soalnya Siapa?

Fazira was born in Sungai Choh, a small town in Rawang, Selangor the first child and the only daughter of Wan Chek and Azizah Zaik.

[2] Fazira was an active student during her school days and developed a passion for acting, which she showed an interest in at a very early age.

In 1998, she went on to embark her first solo concert, Konsert Live Bersama Erra Fazira – Kini which took place at the Dewan Merdeka, Putra World Trade Centre (PWTC; now known as World Trade Centre Kuala Lumpur or WTCKL) and attended by 2,000 fans.

[10][11][12] She is one of few Malaysian artists who contributed a special song titled "Suluhkan Sinar" ("Shine the Light").

Produced by KRU and released in January 2005, the song was specially dedicated to the victims of the 2004 Indian Ocean earthquake and tsunami.

Starting 2001, Fazira began to work with many different directors for her films including Ahmad Idham for Mr. Cinderella (2002) and Abdul Razak Mohaideen for Cinta Kolestrol (2003) among others.

From 2018 to 2021, she became part of the cast member of longest-running Malaysian action drama series, Gerak Khas, playing the role of ASP Jeslina.