Caetani-Lovatelli was born in Rome in 1840 to Michelangelo Caetani, Duke of Sermoneta, Prince of Teano and the Polish Countess Calixta Rzewuska (1810-1842).

Lovatelli was the first woman to become a member of the Accademia Nazionale dei Lincei, which is the oldest Italian scientific academy.

The salon attracted writers and composers such as Stendhal, Honoré de Balzac Nikolai Gogol and Franz Liszt.

Caetani-Lovatelli was interested in archaeology and history and published papers on several subjects.

She talks within the scientific methods required but she pulls in other related and referenced works.