Congenital webs commonly appear in the middle and inferior third of the esophagus, and they are more likely to be circumferential with a central or eccentric orifice.

[citation needed] Clinical symptoms of this condition are selective (solid more than liquids) dysphagia, thoracic pain, nasopharyngeal reflux, aspiration, perforation and food impaction (the last two are very rare).

[citation needed] They are mainly observed in the Plummer–Vinson syndrome,[3] which is associated with chronic iron deficiency anemia.

One in 10 patients with Plummer-Vinson syndrome will eventually develop squamous cell carcinoma of the esophagus,[4] but it is unclear if esophageal webs in and of themselves are a risk factor.

[citation needed] Esophageal webs and rings can be treated with endoscopic dilation.