Esperanza Malchi also spelled Malk or Malkhi (died 1 April 1600) was a Jewish Ottoman businesswoman.
She was the influential favorite and Kira (business agent) of Valide Sultan Safiye.
Esperanza Malchi, in particular, has often been confused with Esther Handali, who had a similar position to her and was active at the same time.
As was common for a kira, she became the trusted confidant of her client, and her tasks soon expanded from acting as intermediary for merchant goods to acting as intermediary for other money transactions, and from there to further tasks between her client and the outside world.
Reportedly, she attempted to influence Safiye (and through her the sultan) to a policy against the Republic of Venice, and by doing so came in conflict with the Venetian spy Beatrice Michiel, who had the opposite intention: the two women once came in to open conflict in front of Safiye.