Between the 1940s until the 1960s, Nesbitt actively led a career as a fashion illustrator for leading magazines and newspapers including Harpers Bazaar, Mademoiselle, and the New York Times Magazine.
[1][2] In the 1960s and 1970s, Nesbitt was one of the earliest artists experimenting with xerox art.
[7] She invent three xerography techniques, named transcapsa, photo-transcapsa, and chromacapsa.
[7] Nesbitt worked closely with Anibal Ambert and Merle English at Xerox Corporation and the company sponsored her art research from 1970 until 1972.
[2] Her work is featured in various public art museum and library collections including, the Museum of Fine Arts, Houston,[9] Brooklyn Museum,[10] Archives of American Art,[11] National Museum of American History,[6] Digital Public Library of America,[12] Smithsonian American Art Museum,[3] Frances Neady collection at Fashion Institute of Technology,[13] among others.