[1] Arango was born in Bogotá, Colombia and moved with his family to the United States in 2000.
He graduated with a bachelor's degree in communications from Florida International University.
[2] After graduating college, Arango worked as a creative producer at the Discovery Channel.
[2] Arango's feature-length debut, Blast Beat, adapted from his 2015 short film of the same name, premiered at the 2020 Sundance Film Festival.
[4] Ponyboi, directed by Arango and written by and starring River Gallo, premiered at the 2024 Sundance Film Festival.