Ester Karuse was born and raised in Valga,[2] where she attended primary and secondary schools.
She is a graduate of the Estonian Entrepreneurship University of Applied Sciences with a degree in business management.
[2] In the 2017 local government council election in Valga Parish, she ran on the list of the Centre Party and achieved the 4th best result in the district with 196 votes and was elected as a member of the Valga municipal council with a list mandate.
Uno Kaskpeit, representing the Conservative People's Party of Estonia (EKRE) received the best result in the district with 3,802 votes.
[7] On 23 March 2023, Karuse's father, Allain Karuse, was convicted in Tartu County Court of offenses against freedom of election during the 2021 Estonian municipal elections and the illegal handling of liquid fuels for which an aggregate punishment of €12,450 was ordered by the court.