Etonitazene 5-cyano analogue (Etocyanazene, 5-cyanodesnitroetonitazene) is a benzimidazole derivative with opioid effects, first developed in the 1950s as part of the research that led to better-known compounds such as etonitazene.

It is an analogue of etonitazene where the 5-nitro (NO2) group has been replaced by a nitrile (C≡N) group.

[1] It is described as having "reduced but still significant" potency compared to etonitazene itself.

[2] It was made illegal in Germany in July 2021.

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