A station at the intersection of Euclid Street (Euclid Avenue from 1870) and Willson Avenue (East 55th Street from 1906[7][8]) first opened in 1856, when Jared V. Willson and his wife executed a quitclaim deed for $1, partitioning their plot of land on the SE corner of the intersection for a small wooden shelter to be built by the Cleveland and Pittsburgh Rail Road.

[9] Additional funds were provided by residents of Euclid Street, contributing $500 towards the construction of said station building.

[14] The final stationhouse opened for service on June 8, 1902, with the previous structure being demolished shortly afterwards to make room for parking on the west side of the station.

This station was made the northern terminal of passenger service after Union Depot closed on September 26, 1953.

[18] The Clevelander began making commuter stops on October 23, 1959, and remaining passenger service to Pittsburgh was truncated to Youngstown after April 25, 1964.