[9][10] After the death of their mother, the three-year-old twins and their older brother Leonid were brought by their father, Semyon (Simon) to New York in December 1979.

[13] Vindman was commissioned as an officer in the United States Army after receiving his bachelor degree and he rose to the rank of colonel.

[13] During the Trump administration in 2018, Vindman was assigned as a deputy legal adviser to the National Security Council (NSC), where he was the senior ethics official.

[21] Eugene helped his brother throughout President Trump's first impeachment, which went from December 18, 2019, to February 5, 2020, including by drafting the portion of the opening statement where Alexander Vindman assured their father that he had made the right decision in emigrating from the Soviet Union to the United States.

[22] Alexander stated, "In Russia, my act of ... offering public testimony involving the President would surely cost me my life.

I am grateful for my father's brave act of hope 40 years ago and for the privilege of being an American citizen and public servant, where I can live free of fear for mine [sic] and my family's safety.

Dad, my sitting here today, in the U.S. Capitol talking to our elected officials is proof that you made the right decision forty years ago to leave the Soviet Union and come here to United States of America in search of a better life for our family.

On February 10, 2020, then-Senate Minority Leader Chuck Schumer (D-NY) sent a letter in an apparent response to the firing of the two brothers that requested federal Inspectors General to investigate possible retaliation against "anyone who has made, or in the future makes, protected disclosures of presidential misconduct".

[23] On February 13, Trump's former chief of staff, retired Marine General John Kelly, defended Vindman's actions and testimony.

[27] Since 2022, Vindman has held the position of Director of Military Analysis and Prosecution Support for the Atrocity Crimes Advisory (ACA) group.

These professionals will collaborate with Ukrainian forces close to the front lines, offering training on mending battle-affected equipment provided by Western countries.

[29] In November 2023, Vindman announced that he would run for the United States House of Representatives in Virginia's 7th District, where incumbent Democrat Abigail Spanberger was not seeking reelection.

[30][31] Vindman received endorsements from Adam Schiff, former Under Secretary of the Army Patrick Murphy, and the editorial board of The Washington Post.

[33][36] In April 2024, Vindman also was criticized on social media after he was photographed alongside supporters in a now-deleted post to Twitter holding a flag used during Virginia's Confederate period.