The First European Symposium took place in 1989 and covered calcium binding proteins in normal and transformed cells.

Long discussions in 1988 between Pochet and Jacques Haiech at Mont Sainte-Odile who pointed out the importance of European researchers in calcium binding proteins (Hamoir, Liége, 1955,[1] Pechere, Montpellier, 1965,[2] Drabikowski, Varsovie, 1970[3]) and the strong support received from Claus Heizmann.

In 1997 they created the group's first ECS Web site,[4] logo, newsletter and a set of statutes published in the “Moniteur belge” as an “Arrêté Royal du 22 septembre 1997” signed by King Albert II.

Since 2000, ECS has been selected as an EU High-level Scientific Conference allowing it to offer grants to young European researchers.

Since 1992 Heizmann has sponsored the publication of significant articles in the scientific journal Biochimica et Biophysica Acta.