Husson studied at the American Film Institute,[3] whose alumni include Andrea Arnold, Terrence Malick and David Lynch.
Her thesis film, Hope to Die, was nominated at the Student Academy award at the American Society of Cinematographers, and screened in several festivals around the world (such as Tribeca, Deauville, Los Angeles).
Scouted in the street at the age of 14, she began her career in cinema as an actress, playing the role of Julie in the movie Les Romantiques, directed by Christian Zarifian in 1994.
Shot in Death Valley in five days with three actors, including her close collaborator Morgan Kibby, it awas shown in many festivals around the world and on the French/German TV channel Arte in 2014.
[8] In 2021, Husson directed Mothering Sunday, starring Odessa Young, Josh O'Connor, Colin Firth and Olivia Colman.