Middleton began her career working with non-governmental organizations promoting breastfeeding and later served as a polyclinic administrator.
[1][2] BIB helped promote breastfeeding with new mothers, provided information and breast pump rental.
[5] Middleton became a leader and driving force behind the disability rights organization, the Belize Assembly for Persons with Diverse Abilities (BAPDA).
[6] As an advocate, she made multiple calls to Belize morning shows, sharing various activities carried out by BAPDA.
[7] Later, Middleton co-founded create Living Independently in Full Existence (LIFE), an organization to aid the elderly in the country.