[10] He was able to break out of that slump with 27 points, four assists, and three rebounds in a win over the La Salle Greenies, earning a Player of the Week award in the process.
[13] In a game against the JRU Light Bombers, he made two clutch free throws and a fastbreak layup with .3 seconds remaining to finish with 19 points and a one-point win.
[14] The Red Cubs didn't make the Finals after they were upset by the Greenies in triple overtime, despite his 26 points, 11 rebounds, eight assists and all while battling cramps.
[18] He also played in his final SLAM Rising Stars Classic, winning co-MVP honors with a younger Kai Sotto.
[25] Nelle started San Beda's title defense with a win over the Arellano Chiefs in which he had nine points, five rebounds, and five assists.
[30] In San Beda's sixth straight win of the season, he scored 12 points and four assists against the Perpetual Altas.
[31] In San Beda's seventh straight win, he scored nine of his 14 points in the fourth, along with seven assists and four rebounds to prevent the Lyceum Pirates from breaking the streak.
[36][1] He joined teammates Kwekuteye and Calvin Oftana (who was awarded as that season's MVP) on the NCAA Mythical Team.
[37] With the championship on the line in Game 3, he exchanged clutch shots with Letran's Fran Yu, including a three-pointer that brought San Beda to within two points with 11.5 seconds remaining.
[41] He also revealed that the coaching staff also didn't contact him for a month, and that he had also gotten into an argument with the team manager when practices resumed.
[43] Mark Nonoy, a UAAP Rookie of the Year winner from the UST Growling Tigers, joined him to form a new backcourt tandem.
[48] Against the Adamson Soaring Falcons, he made a clutch three-pointer that helped La Salle seal the win.
In the offseason, Nelle was originally gonna miss DLSU's inaugural campaign in the 2022 PBA D-League Aspirants' Cup for personal reasons.
[58] Season 85 saw DLSU bolstered by the addition of Kevin Quiambao, who had led them in their PBA D-League title campaign.
[63] Against Adamson, he had a near triple-double of nine points, eight boards, and nine assists, but got his third unsportsmanlike foul of the season and missed a game-winning layup in double OT.
[71] After Lastimosa made two free throws, he had a chance to tie the game, but he rushed his three-pointer and the ball hit the side of the backboard.
[73] Although he finished in the top 5 in statistical points and could have made the Mythical Team, he was disqualified due to his one-game suspension.
[75] After La Salle announced that they would have a new head coach with Topex Robinson replacing Derrick Pumaren, Nelle decided to stay for his final season.
He also led them to another PBA D-League title despite getting injured with 16 points, 5 rebounds, 7 assists, and 6 steals in the championship game against his former team San Beda.
[81] Against Adamson he scored six of his 12 points in a 23–0 third quarter run that led to the Archers' third win of the season and the second seed.
[87] Although he struggled in a rematch with UE, his teammates Quiambao and Nonoy stepped up as the former grabbed his 2nd triple-double of the season while the latter scored a season-high 25 points to win their sixth straight game.
[89] As he averaged 11.3 points, 6.9 assists, 5.0 rebounds, and 2.0 steals, he was awarded a spot on the UAAP's Mythical Team alongside Quiambao, who won MVP.
[91] He shot a poor 2-of-12 from the field for just four points in Game 2, but still made an impact with 12 rebounds, 10 assists while also getting five steals and was also a plus-20 on the court as DLSU bounced back.