Ziporyn studied at Eastman, Yale and UC Berkeley with Joseph Schwantner, Martin Bresnick, and Gerard Grisey.
His involvement with BOAC continued for 25 years: in 1992 he co-founded the Bang on a Can All-stars (Musical America's 2005 Ensemble of the Year), with whom he toured the globe and premiered over 100 commissioned works, collaborating with Nik Bartsch, Iva Bittova, Don Byron, Ornette Coleman, Brian Eno, Philip Glass, Meredith Monk, Thurston Moore, Terry Riley and Tan Dun.
He left the group in the fall of that year to form Eviyan with Iva Bittová and Gyan Riley, with whom he now concertizes and records regularly.
In the fall of 2013 he founded the Critical Band, a group devoted to the music of the late British composer Steve Martland.
These include three evening-length works, 2001's ShadowBang, 2004's Oedipus Rex at the American Repertory Theater (Robert Woodruff, director),[2] and 2009's A House in Bali, an opera about composer Colin McPhee, anthropologist Margaret Mead, and artist Walter Spies, which joined Western singers Anne Harley, Marc Molomot and Timur Bekbosunov with Balinese traditional performers Nyoman Catra and Desak Made Suari Laksmi, and Bang on a Can All Stars with a full gamelan ensemble.
As a clarinetist, Ziporyn recorded the definitive version of Steve Reich's multi-clarinet New York Counterpoint in 1996, sharing in that ensemble's Grammy Award in 1998.
His honors include awards from the Massachusetts Cultural Council (2011), The Herb Alpert Foundation (2011), USA Artists Walker Fellowship (2007), MIT's Kepes Prize (2006), the American Academy of Arts and Letters Goddard Lieberson Fellowship (2004), as well as commissions from Meet the Composer/Commissioning Music USA and the Rockefeller MAP Fund.