Popadinova has played for Sportika Blagoevgrad in her home country before moving to England to sign with Bristol Academy.

[5] In 2016, Popadinova enrolled at the University of Northwestern Ohio to play for their Division II NAIA program.

Following two years with the Racers, Popadinova transferred to play with the Florida Gulf Coast Eagles in NCAA Division I.

[6] Ahead of her senior season, Popadinova was named on the MAC Hermann Trophy watchlist, one of only two players from her conference.

[8] At age 16, Popadinova made her senior debut for Bulgaria on 20 August 2013, coming on as a substitute to score in the 4–2 away win over Macedonia in a friendly match.