Valya Harkonnen, portrayed by Emily Watson, is the Mother Superior of the Sisterhood, a secretive, matriarchal order whose members undergo intense physical training and mental conditioning to obtain superhuman abilities.
[6] She plots to rise within, and ultimately take control of, the fledgling Bene Gesserit, while galvanizing her siblings to help her visit Harkonnen vengeance on the bloodline of Vorian Atreides, who had brought their family to ruin 80 years before.
[2] In the series premiere "The Hidden Hand", young Tula Harkonnen has followed her elder sister and joined the Sisterhood on Wallach IX to escape her family's exile to a desolate world.
In the past, Valya and Tula's brother, Griffin Harkonnen, is killed, allegedly murdered by Vorian Atreides, the man responsible for their family's downfall.
Having discovered direct descendants of Vorian Atreides living on the planet Caladan, Valya sends her younger sister, using the alias Tula Veil, to exact their revenge.
Desmond Hart, portrayed by Travis Fimmel, is a mysterious, charismatic soldier in the Imperial army who seeks the trust of the Emperor, and emerges as an enemy to the Sisterhood.
"[13] In "The Hidden Hand", renowned soldier Desmond Hart appears on the capital world of Salusa Secundus, having survived an attack on the Imperial mining operations on the desert planet Arrakis attributed to the native Fremen.
He reveals to Emperor Javicco Corrino that the assault was in fact perpetrated by rebellious forces growing against him, and suggests that the "witches" of the Sisterhood may be intentionally not keeping him informed.
Arriving unexpectedly at the palace, Mother Superior Valya Harkonnen sees through Javicco's attempt to hide Desmond's guilt, and secures permission to interrogate him.
Natalya is suspect of Valya's motives, but by design, Javicco requires Richese ships to maintain his control of the Arrakis, only source of the all-important spice.
During the engagement celebration, Natalya is horrified by Pruwet's possession of forbidden technology in the form of a robotic toy lizard, and his father Duke Ferdinand Richese's flippant acceptance of it.
She angrily reminds the Duke that he only exists because the Corrinos defeated the thinking machines, and is shocked speechless when Javicco declares he will ignore the transgression for the evening.
"[16] In "The Hidden Hand", Princess Ynez is the heir to the Golden Lion Throne, training in swordplay under Corrino Swordmaster Kieran Atriedes, and preparing to enter the Sisterhood as an acolyte.
Her departure delayed, Ynez has a close moment with Keiran, and tells him about how she and her illegitimate half-brother, Constantine Corrino, were kidnapped and held captive by rebels as children.
While Mother Superior Valya describes her as "a lamb lost in the woods", Tula notes that Lila is a "true empath" who needs to be nurtured, and that "given her lineage, she will be a natural born Truthsayer."
In "Two Wolves", Keiran is revealed to be a direct descendant of Vorian Atreides, as well as a spy for a faction of insurgents plotting against Emperor Javicco and the Great Houses.
"[16] In "The Hidden Hand", Mikaela is a bartender at the nightclub where Princess Ynez and her illegitimate half-brother, Constantine Corrino, go on the eve of her departure to Wallach IX to be trained by the Sisterhood.
When Mother Superior Valya informs her that the Sisterhood now needs to bolster Javicco, Mikaela is surprised but readily offers to burn the entire resistance cell, starting with Kieran.
Javicco's seven-year-old sister, Nantha, is killed in Mentats of Dune, trampled to death by an anti-technology mob incited by demagogue Manford Torondo.
[18] Sister Jen, portrayed by Faoileann Cunningham, is "a fierce, unpredictable acolyte in training at the Sisterhood School who rarely reveals her emotional core.
[16] Sister Emeline, portrayed by Aoife Hinds, is "a zealous acolyte descended from a long line of martyrs, who carries fervent religion to her training at the Sisterhood.
Emeline reveals that her family fought with Rayna Butler in the Battle of Corrin, and sacrificed themselves to allow time for the human fleet to destroy the thinking machine army with atomics.
After meeting the mysterious Imperial soldier Desmond Hart, Kasha has unsettling visions that involve Ynez, and comes to believe that the marriage, orchestrated by Mother Superior Valya, should not proceed.
On Salusa Secundus, Desmond suggests to Javicco that the "witches" of the Sisterhood are keeping him in the dark about growing insurgency against him, but the Emperor insists that Kasha has never led him astray.
"[12] In "The Hidden Hand", Dorotea and Valya are at a dying Raquella's bedside to hear her final words, urging them to "use every tool" to grow, protect and strengthen the Sisterhood after her death.
Mysterious Imperial soldier Desmond Hart, who perceives the Sisterhood as a growing threat to the autonomy of the Imperium, uses a "great power" granted to him by his near-death experience on Arrakis to psychically immolate Ynez's betrothed, Pruwet Richese.
"Sisterhood Above All" depicts Raquella meeting and taking Valya under her wing, eventually sharing with her the secret of the forbidden technology used to maintain her vast DNA database.
Already displeased with the engagement, Empress Natalya is horrified by Pruwet's possession of forbidden technology in the form of a robotic toy lizard, and Ferdinand's flippant acceptance of it.
She angrily reminds the Duke that he only exists because the Corrinos defeated the thinking machines, and is shocked speechless when Javicco declares he will ignore the transgression for the evening.
Already displeased with the engagement, Empress Natalya is horrified by Pruwet's possession of forbidden technology in the form of a robotic toy lizard, and Ferdinand's flippant acceptance of it.