Evripidis Stylianidis was born on 8 April 1966 in Maroneia, near Komotini in the Rhodope regional unit of Thrace.

Between 1984 and 1989 he studied at the Law School of the Democritus University of Thrace in Komotini, graduating with a Bachelor's degree.

Between 1995 and 1996 he was an advisor to the president of the New Democracy political party in Greece in issues concerning youth affairs and cultural diplomacy.

Evripidis Stylianidis first entered politics in 1994 with New Democracy as a Member of the European Parliament nominee.

On 19 September 2007, Evripidis Stylianidis became the Minister for National Education and Religious Affairs.