Savage Bees was licensed to Memetron originally for its North American release.

[3] A reviewer of Gamest Mook noted that the insect and skull-themed enemies, the inorganic backgrounds, as well as the mysterious and anxiety-inducing music posed a unique and exciting atmosphere.

He also praised the mechanic of turning enemies into collectable fruit items as "the greatest attraction" for this title.

This game was released for the Wii Virtual Console Arcade in Japan on September 21, 2010, and in the PAL region and North America in January 2011.

[6] Colonel Issue appears as a cameo character in Project X Zone 2 as part of Captain Commando's Solo Unit attack.