[2] Their status as imprisoned human subjects becomes even more ethically problematic when investigators offer incentives such as parole, phone calls, or objects that are normally unavailable to prisoners.
[citation needed] In Japan, Unit 731, located near Harbin (Manchukuo), experimented with prisoner vivisection, dismemberment and induced epidemics on a very large scale from 1935 to 1945 during the Second Sino-Japanese War.
[citation needed] Project MKUltra was a CIA-run human experiment program from 1953–1973 where volunteers, prisoners and unwitting subjects were administered hallucinogenic drugs in an attempt to develop incapacitating substances and chemical mind control agents, in an operation run by Sidney Gottlieb.
[4] Experiments included high-risk cancer treatments, the application of strong skin creams, new cosmetics, dioxin and high doses of LSD.
[5] American oncologist Chester M. Southam injected HeLa cells into Ohio State Penitentiary inmates without informed consent in order to see if people could become immune to cancer.
[6] The Herero and Namaqua Genocide in present-day Namibia, in Southern Africa, resulted in a large number of prisoners in concentration camps.