Acres of Skin: Human Experiments at Holmesburg Prison is a 1998 book by Allen Hornblum.

The book documents clinical non-therapeutic medical experiments on prison inmates at Holmesburg Prison in Philadelphia from 1951 to 1974, conducted under the direction of dermatologist Albert Kligman.

[2] The book discusses issues surrounding the inadequate consent procedures of the 1950s and 1960s when using prisoners.

Prisoners, attracted by the compensation, were angry when two of the experiment's participants testified before Congress.

[3] The publication of Acres of Skin in 1998 attracted considerable international media interest.