Located on the outskirts of the Holosiiv Forest, a large portion of which has been converted into a park zone, the expo specializes in demonstrating Ukrainian achievements in the sphere of industry, science etc.

In 1949, the USSR Council of Ministers signed the statute for the construction of facilities for a Republic Agricultural Exhibition in Kyiv.

It was built on the site of a small suburban village called Krasny traktir (English: Red Tavern).

Nikolai Podgorny, the first secretary of the Central Committee of the Communist Party of Ukraine, personally cut the red ribbon.

During the existence of the exhibition, it has been visited by world-famous people: Charles De Gaulle, Josip Broz Tito, Margaret Thatcher and others.

On July 20, 2017, there was held a public presentation of the concept of development of the Expocenter for the next 40 years, and the wife of the former President of Ukraine Maryna Poroshenko attended it.