Expressway S52 is a Polish highway under construction with a planned length of 116 km (72 mi), located in the Silesian and Lesser Poland voivodeships.

Upon completion it will connect the border of the Czech Republic in Cieszyn (along with the D48 motorway) with Kraków.

[1] The separate section also numbered S52 is the northern bypass of Kraków, which is completed since 2024.

Before 2016, the section from Bielsko-Biała to the state border in Cieszyn was part of the expressway S1.

From 1999 to 2004, the first constructed section of Kraków northern bypass (from interchange with A4 in Balice to Modlniczka) was designated as the A41 motorway,[2] although the route number was not shown on maps and road atlases at that time.