Extended-release morphine

Brand names for this formulation of morphine include Avinza,[1] Kadian,[1] MS Contin,[1] MST Continus,[2][3][4][5] Morphagesic, Zomorph, Filnarine, MXL,[6] Malfin, Contalgin, Dolcontin, and DepoDur.

Unlike the MS Contin brand and its generic versions, Kadian and Avinza are designed to be 12- to 24-hour release, not 8- to 12-hour.

MST Continus[2][3][4] and MXL[6] are registered copyright and trademark of Napp Pharmaceuticals and are available in the UK.

The plastic spheres containing powder have micropores that open at varying pH levels, to maintain a mostly constant release during transit through the digestive tract.

[citation needed] Other brands are thought to use ethylcellulose coatings to control drug release from pellets.