As a player he was an attacking midfielder who spent most of his career in England playing in the Premier League for Southampton, West Ham United, Blackburn Rovers, Manchester City and Portsmouth.

Following retirement he was appointed as general manager of Maccabi Netanya and later held a similar position of Hapoel Tel Aviv.

His performances for the club earned him a call-up to the Israel national team as well as the Most Valuable Player award for the 1993–94 season.

[18] He played for the Scottish club for two years, scoring ten goals, but Martin O'Neill left him out of the team when he took over as manager and Berkovic returned to England to join Blackburn Rovers on loan for the second half of the 2000–01 season, where he scored twice against Queens Park Rangers[19] and Grimsby,[20] helping Blackburn achieve promotion to the Premier League in the process.

When Berkovic returned, the City team began to play with both playmakers in a 3–5–2 formation with Kevin Horlock operating in the anchor midfield position.

Berkovic received abuse from some of the City support when he made a 'throat-slitting' gesture to a female fan during a League Cup tie at Maine Road against Crewe Alexandra.

Berkovic soon established himself in the first team at Fratton Park where he was reunited with his former manager at West Ham, Redknapp, who described him as a "special footballer".

[26] Berkovic became a vital part of Portsmouth's drive for FA Premier League survival, scoring his first goal against Tottenham Hotspur.

The return to Israel opened with promise as the 2005–06 season was the 100th anniversary for Maccabi Tel Aviv and the club wanted to celebrate with a championship.

Although the team had a positive start to the season, they were not able to sustain good form and their chances of winning the title diminished, resulting in a sacking of the coach Nir Klinger,[32] who was replaced with Ton Caanen.

[33] In November 2017, the two began to present a weekly television show on Friday evenings, called Ofira and Berkovic, on Keshet Channel 12.

He stated that he left the job due to poor professional relations with Daniel Jammer, the club's owner and chairman.

[36] Berkovic had been an active manager in the transfer market during his two months, signing 15 players including Mazuwa Nsumbu, Liran Strauber and Itay Shechter.