After one season back at the third level, Denderhoutem merged with fellow club KFC Denderleeuw EH from the third division.

They won promotion back to the second tier, now renamed the Challenger Pro League, in the 2021–22 season.

The following day, it was announced that Liège would receive a three-point deduction and a €1000 fine after failing to field enough U21 players in their 3–0 win against Dender back in March 2022.

This is because Liège lost on the final game of the season against Knokke, while Dender won 1–0 against Dessel Sport.

[9] Before the start of the season, the club was dealt with the blow of the departure of manager Timmy Simons who left to join fellow top tier side Westerlo.

[11] Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.