Although the education wing was demolished to make room for the tower, the remainder of the former church building has been preserved and has since been re-purposed into Daniels Recital Hall.

[9] F5 Tower was designed by ZGF Architects with angular glass curtain walls that mimic the silhouette of actress Audrey Hepburn as she appears in the 1961 film Breakfast at Tiffany's.

[10] The glass walls of the building were designed to regulate temperature and energy use by letting in some sun rays and reflecting others.

[11] To achieve LEED Silver standards, the tower will have a system to capture rainwater for reuse, a 35-foot-tall (11 m) "living wall" where plants grow in a Columbia Street façade, and rooftop solar energy equipment.[5][when?]

The exterior elevator was somewhere between the 33rd and 37th floors when high winds caused a power cord to slip and catch on a fall protection net outrigger.

[20] The building was closed to all workers and visitors on March 2, 2020, for large-scale cleaning after an F5 employee had come into contact with a person carrying COVID-19 coronavirus.