The FIDE Women's Grand Swiss Tournament 2021 was a chess tournament, FIDE Women's Grand Swiss Tournament, that forms part of the qualification cycle for the Women's World Chess Championship 2022.

It was an 11-round Swiss-system tournament, with up to 50 players competing, ran from 27 October to 7 November 2021 in Riga, Latvia, in parallel with the FIDE Grand Swiss Tournament 2021.

[1] It was the first FIDE Women's Grand Swiss Tournament.

[3] The top four qualifiers by rating declined their invitations, including Aleksandra Goryachkina, Koneru Humpy and Ju Wenjun, who have no need to play, either through being Women's World Champion (Ju Wenjun), or having already qualified for the 2022 Women's Candidates Tournament.

Goryachkina is instead playing in the Open Grand Swiss Tournament.