1JCQ, 1LD7, 1LD8, 1MZC, 1S63, 1SA4, 1TN6, 2F0Y, 2H6F, 2H6G, 2H6H, 2H6I, 2IEJ, 3E37233914272ENSG00000168522ENSMUSG00000015994P49354Q61239NM_001018676NM_001018677NM_002027NM_008033NP_002018NP_032059Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha is an enzyme that in humans is encoded by the FNTA gene.

[5][6] Prenyltransferases attach either a farnesyl group or a geranylgeranyl group in thioether linkage to the cysteine residue of protein's with a C-terminal CAAX box.

This gene encodes the alpha subunit of these transferases.

Alternative splicing results in multiple transcript variants encoding different isoforms.

[6] FNTA has been shown to interact with TGF beta receptor 1.