[1] Maidana was born on 22 June 1992 in Margarita, Santa Fe, and from a young age aimed to follow in his brother's footsteps as a boxer.

[2] Maidana made his professional debut on 21 June 2014, defeating Eddie Diaz by unanimous decision on the undercard of the Vasyl Lomachenko–Gary Russell Jr. title fight at the StubHub Center.

[14][15] After eight straight wins in the United States, Maidana competed in Argentina for the first time, defeating Andrés Amarilla by unanimous decision in Necochea on 9 April 2016.

[17] On 26 November 2016, in just his second fight on home soil, Maidana captured the WBA Fedebol super welterweight title with a second-round TKO of Cristian Romero.

[20] Ryan Songalia of The Ring wrote that, although he didn't possess the punching power of his older brother, he had "quicker hands and snappier combinations.