Fabian Sebastian Gaffke (August 5, 1913 – February 8, 1992) was an American right fielder who played in Major League Baseball between 1936 and 1942 for the Boston Red Sox (1936–39) and Cleveland Indians (1941–42).

Listed at 5 ft 10 in (1.78 m), 185 lb., Gaffke batted and threw right-handed.

In a six-season career, Gaffke was a .227 hitter (73-for-321) with seven home runs and 42 RBI in 129 games, including 43 runs, 14 doubles, four triples, and two stolen bases.

Gaffke died in his homeland of Milwaukee, Wisconsin at age 78.

This biographical article relating to an American baseball outfielder born in the 1910s is a stub.