Members of this gens are known from the early third century BC down to the end of the Republic, but they seldom attained positions of importance in the Roman state.
The first Fabricius who occurs in history is the celebrated Gaius Fabricius Luscinus, who distinguished himself in the war against Pyrrhus, and who was probably the first of the Fabricii who left his native place and settled at Rome.
We know that in 306 BC, shortly before the war with Pyrrhus, most of the Hernician towns revolted against Rome, but were subdued and compelled to accept the Roman franchise without suffrage.
Gaius Fabricius Luscinus probably left Aletrium either at that time or soon after, and settled at Rome, where, like other settlers from isopolite towns, he soon rose to high honours.
Besides this Fabricius, no members of his family appear to have risen to any eminence at Rome; and we must conclude that they were either men of inferior talent, or what is more probable, that being strangers, they laboured under great disadvantages, and that the jealousy of the illustrious Roman families, plebeian as well as patrician, kept them down, and prevented their maintaining the position which their sire had gained.