The film stars Helmut Berger as Dr. Flamand, Brigitte Lahaie as Nathalie, Christopher Mitchum as Sam Morgan, and Stéphane Audran.

In the film, Dr. Flamand and his assistant Nathalie lure unsuspecting victims to use their skin to perform plastic surgery on the doctor's disfigured sister.

A New York businessman hires private detective Sam Morgan to find his missing fashion model daughter.

It was released theatrically in Paris and received lukewarm reviews from French genre magazine Mad Movies and a negative one from Variety.

At a photoshoot in Paris, the doctor's assistant and lover Nathalie kidnaps the American model Barbara Hallen.

In New York City, Barbara's father Terry Hallen hires her ex-boyfriend, the private detective Sam Morgan, to find her.

Morgan traces a credit card belonging to Barbara to the Paris suburb of Saint-Cloud and to Flamand's clinic.

[2][8] It was the first feature film director Jesús Franco made with an international cast and a full sized-crew in nearly 20 years.

Toullec found that fans of horror films will appreciate the variety of instruments used to create gory special effects.

[15] In the same publication, Marcel Burel also complimented the effects while finding it had an American made-for-television film quality of dialogue.

[16] The "incredibly gory" film was deemed one of Franco's most "effective" and "technically competent efforts" by Jay Slater of Rue Morgue.

[17] Jeffrey Kaufmann of Blu-ray.com noted the film's "over the top" gore effects ranged from silly to effective and concluded, "Faceless is just flat out goofy a lot of the time, and with a cast that kind of has to be seen to be believed (and maybe not even then), this has the expected amount of Franco-esque titillation combined with occasional bursts of Grand Guignol weirdness.