The story focuses on a group of children who pilot the titular Fafners in an escalating war against giant aliens called Festum.

At the beginning of the Dead Aggressor story arc, much of the world has been destroyed by the Festum and the remote Japanese island of Tatsumiyajima (竜宮島, lit.

The island's young people continue with their daily lives unaware of these events, but after many years of peace, a lone Festum discovers Tatsumiya and attacks.

In desperation, they order the deployment of a mecha called the Fafner Mark Elf, but its pilot is killed en route to the hangar.

Left with no further options, they send a young boy named Kazuki Makabe as the replacement pilot assisted by Sōshi Minashiro from within the Siegfried System.

It is also revealed that the cloaking was not meant to conceal Tatsumiya Island from only the Festum, but from the rest of humanity who would seek to use its technology in the greater war against them.

Yumi Ikoma and Ryou Masaoka are children who have been selected to take part in a top secret mission, to be the pilots of the first Fafner combat units; the last chance of survival for the human race.

Two years after the end of the original Fafner in the Azure TV series, Tatsumiya Island and its surviving residents have returned to some semblance of recovery.

With Misao's arrival, hostilities break out anew between the Human Army and the Festum, and the Fafner pilots are thrown into the most desperate battle of their lives - this time, with the fate of TWO races riding on their shoulders.

When the two meet, they will open the door to a new world... Fafner in the Azure: Dead Aggressor aired on TV Tokyo from July 4, 2004, to December 26, 2004.

A film, titled Fafner in the Azure: Dead Aggressor: Heaven and Earth premiered in Japan on December 25, 2010.

A twitvideo post from lead vocalist Atsuko announced that a sequel to the Fafner in the Azure series has been green-lit for production.

The sequel, titled, Fafner in the Azure: Dead Aggressor -EXODUS-, aired on MBS and several other stations from January 8, 2015, to December 26, 2015.

[12] On December 27, 2021, a 53-minute spinoff episode titled Fafner in the Azure: Behind the Line was announced, featuring the returning staff and cast.

[17] A novelization of the Dead Agressor series written by Tow Ubukata and featuring illustrations by Hisashi Hirai was published on January 10, 2005.

A "complete version" of the story, adapted from the original anime, its light novel, drama CDs, and stage play.

Japanese band angela consistently write and perform all of Fafner's opening, insert and ending theme songs that achieve strong sales and popularity.

It returned in 2013 in Super Robot Wars UX for the Nintendo 3DS, which also marks the debut of the series' movie sequel, Heaven and Earth.