Faint little ball

[4] Drosophila EGF receptor is involved in the development of embryos as well as larvae/pupae's wings, eyes, legs and ovaries.

[1] When DER is over utilized in the cell because of increases in ligand, phenotypic abnormalities can be visualized such as hyperplasia of the head midline structures.

Rhomboid is a protease that cleaves ligands such as Spitz so that they can come into contact with receptors such as DER and begin activate a signal transduction pathway.

At six hours the gene is used to differentiate epidermal cells to secrete denticle belts which begin segmentation of the larva.

[4] When this gene is mutated or any of its interactions are altered phenotypes such as fused commissures can be seen as a result of improper segregation.

Since flb plays a role in the formation of the CNS and the eye, head structures will be underdeveloped or not present at all.