Falls Creek was established in the summer of 1917, when J.B. Rounds and W. D. Moorer used donated land to host the meeting of the Baptist Young People's Union, with a total of 273 campers.

The geologic formations surrounding Falls Creek have been dated to the Ordovician and contain many fossils of organisms that lived during that time.

A large graben is present in the camp which contains the clastic materials of the Royer Dolomite which underwent karsting and was redeposited during the Pennsylvanian as the Collins Ranch Conglomerate.

Since 1947,[4] Falls Creek has hosted a special annual gathering, called "Indian Falls Creek", of Native American Christians from Christian churches of all denominations across and outside of the United States, and from many churches residing within the state of Oklahoma.

[8][9] In August 2010, a 20-year-old camper from Wichita, Kansas named Moses Fitchpatrick broke off from his hiking group and went missing.

His body was found several days later, two miles south of the Falls Creek property, in rough terrain.