His younger brother Jan and sister Rita are less gifted and often feel pushed back, but are nevertheless proud of their sibling.
Once the children are starting their own family lives, shocking news arrives: Anna is pregnant again and Pierre has been diagnosed with a terminal disease.
Guido has successfully founded the VDB Systems electronics company, is married to the eccentric Marie-Rose De Putter and has two children: Peter and Veronique.
On the day little Lovely finally arrives, fate strikes as Marleen gets fatally hit by a car while crossing the street.
Ben has a hard time raising Lovely as a single father, but gets close help of Anna and her new live companion Albert.
The family embraces her again and keeps a close eye on her, but cannot prevent her from a handful returns to drinking, such as the one following her divorce from Rob.
Unfortunately his personal life takes quite a few hits, such as his divorce from the adulterous Marie-Rose and the alleged death of their son Peter.
Guido survives multiple murder attempts by his professional enemy Didier De Kunst, yet one of those makes him end up in a wheelchair for many years to follow.
Luck seems to get back to his side when Peter turns out to be alive, but shortly after this joyful event, Guido dies following a stabbing incident.
In March 2022 both Peter and Marie-Rose die in a house fire and Victor is now being raised by family friends Mathias Moelaert and Vanessa Mariën.
His professional life highlights when he gets appointed mayor, yet after his return to VDB he keeps getting downgraded until he decides to quit and take over the local café.
After an accident, she suffers a change in personality, leading her to quit welfare and start a business career at VDB.
Back in 2002, Anna discovered that her late husband cheated on her with a German woman during World War II and had fathered a child; Georges Van den Bossche.
When Jan goes to Germany to learn more about Georges, he finds out that he died not too long ago and that he also has a child; the shy and introverted Bert Van den Bossche.
Bert wants revenge and sets the business on fire during a party, with the intention of killing Peter and the other major shareholders.
Bert wants to flee to Asia, undergo plastic surgery there and then come back as someone else in order to start his big revenge plan.
Unknowingly to Bert however, Stan double crosses him by making a deal with the captain to dump the container in the ocean.
In 2021 it was revealed in the Familie spin-off book 'Alter Ego' that Bert turned out to have survived his ordeal on the containership and that he had gone to South-Africa instead to undergo plastic surgery and take on a completely new identity.
He starts a relationship with Mieke, who's still unaware of his intentions and true identity, and suggests to organize a big family reunion.