Frances[1] Perkins Andrews Shepard (14 July 1856 – 4 June 1920)[2] was an American physician who worked as a missionary and university lecturer in Turkey.

She made a scientifically significant botanical collection in and around the area where she lived, sending these specimens to George Edward Post, thus assisting with his publication The Flora of Syria, Palestine and Sinai.

[3] In 1882, Shepard moved to the Ottoman Empire with her husband, and supported his work at the Azariah Smith Medical Hospital attached to Central Turkey College in Aintab.

[7] Shepard then worked with her sister Lucy C. Andrews to establish a market for the lace and needlework.

[8][9] Her sister, after a visit to Turkey, returned to the United States with samples of the lace and needlework, and supplied American businesses with these products.