FM 359 heads in a northwesterly direction through Pecan Grove and Fulshear to Interstate 10 at Brookshire in Waller County.

The highway immediately crosses the Union Pacific Railroad tracks and heads 2.2 miles (3.5 km) north through Pecan Grove.

After proceeding northwest, FM 359 passes through the rural community of Foster and turns in a northerly direction.

In this portion of the highway, there is an historical marker at the site of Pittsville near Hunt Road, 2.8 miles (4.5 km) north of Fulshear.

After an additional 1.2 miles (1.9 km), FM 359 ends at a limited access highway interchange with US 290 and SH 6 to the east of Hempstead.

On the same day, the order was amended to extend the highway northwest through Brookshire to SH 6 southeast of Hempstead.