The Farmers and Mechanics Bank of Middletown, Connecticut is a former bank that operated from 1858 to 1996, when it was incorporated into Citizens Bank of Connecticut.

[2] The bank building was built in 1920.

[3] The bank was founded in 1858; medical Dr. William B. Casey was its first president.

It served workers at nearby brownstone quarries, including many Irish immigrants.

[2] The building is a contributing building in the National Register of Historic Places-listed Main Street Historic District.