Augustus Muller S.J, a German Jesuit priest dispensed homeopathic medicines under a Banyan tree.

[citation needed] The college is fully run by the Diocese of Mangalore with its president being Most Rev.

Students and interns posted in the Department of Community Medicine undergo postings at public health centres in Surathkal and Jeppu as well as rural hospitals in Belthangady, Badyar in Dakshina Kannada district and Honnavar, Uttara Kannada district.

The college conducts regular health camps from in far-flung areas in and around Dakshina Kannada and Udupi districts.

The college offers a four-and-a-half-year MBBS course affiliated to Rajiv Gandhi University of Health Sciences with a one-year compulsory rotating internship.

Postgraduate degree (MD/MS) and diploma in specialties which include Medicine, Surgery, Paediatrics, Obstetrics and Gynaecology, ENT, Ophthalmology, Orthopaedics, Radio-diagnosis, Psychiatry and Pathology and master's degree (M.Sc) in Hospital Administration.

The one event that manages to capture the imagination of the Mullerians is the yearly interclass competition, named "Big Bang" in 2003, "The Quest" in 2004, "The Arena" in 2005, "The Conquest" in 2006, "The Apocalypse" in 2007, "Chakravyuh" in 2008, "Argonautica" in 2009 and "Solaris" in 2010.

The college organises sporting events which include Football, Basketball, Throwball, Volleyball, Badminton, Table-Tennis and athletic meet "Velocity" at interclass and intercollegiate level (RGUHS Mysore Zone tournaments).