Fatima Soltan (Volga Türki and Persian: فاطمه سلطان; died 1681) was a sovereign khanbika (queen) and the last ruler of the Qasim Khanate from 1679 until 1681.
She was a daughter of Agha Muhammad Shah Quli Sayyid and a wife of Arslanghali khan.
After the death of her husband in 1627 Russian tsar Mikhail Romanov appointed her and her father Agha Muhammad as regents of her three-year-old son Sayed Borhan.
Until Borhan abdicated in 1679 Fatima Soltan resisted his marriage to a Russian princess and the policy of Christianization and discrimination against Muslims by Moscow authorities.
After Borhan abdicated, she remained briefly in power as the last queen of the Khanate.