[4] After the compulsory military service, Calderazzo joined the research group of Giulio Natta, a future Nobel laureate in Milan.

[5] He made seminal contributions to the mechanism of migratory insertion reactions, with emphasis on the stereochemical course of the carbonylation of CH3Mn(CO)5.

[8][9] Calderazzo extended his interest in carbonyl chemistry of the late transition metals halides.

[15] Calderazzo was a member of the editorial or advisor board of international scientific journals.

He was a member of the Société Royale de Chemie (1987), Società Chimica Italiana and Accademia Nazionale dei Lincei (1989).